B vitamins optimize cell functionPrint
B vitamins are often thought of as energy vitamins. People tend to look for them in drinks and nutrient
bars for a mental or physical energy boost.
Few realize the crucial roles that B vitamins play in the body.
Research has shown that B vitamins are necessary for:1
- DNA/RNA synthesis and repair,
- Proper immune function,
- Neurotransmitter synthesis, and
- Healthy DNA methylation. Adults with a low B-vitamin status are at increased risk for developing age-related disorders, particularly cognitive and cardiovascular disease.1
Vitamin B3 exists in several forms that can convert into nicotinamide adenine dinucleotide (NAD+) in the body.7,8 NAD+ is a cofactor for life-sustaining reactions in the body, and has garnered a reputation worldwide for its potential longevity benefits.9
Studies have also shown that vitamin B3 in the form of nicotinamide has the potential to treat a variety of dermatological conditions, including skin cancer.10,11 One clinical trial included 386 individuals with a history of at least two non-melanoma skin cancers in the previous five years. They were randomly assigned to receive 500 mg of nicotinamide twice daily or a placebo. At 12 months, the rate of non-melanoma skin cancers was reduced by 23% in those receiving nicotinamide, compared to those who got the placebo.11
It has been suggested that nicotinamide’s role in skin cancer may be related in part to its ability to promote NAD+ synthesis, thereby enhancing DNA repair. NAD+ is involved in the synthesis of ATP, the cellular energy currency that is much needed during energy-dependent cellular processes, including DNA repair.10
B vitamins are necessary for DNA repair and synthesis, proper immune function, neurotransmitter synthesis, and healthy DNA methylation.
B vitamins are essential for multiple cellular functions, including facilitating vital DNA repair.
These benefits can be attained through regular use of a high-quality multivitamin, or taking a comprehensive B-complex supplement, preferably one that uses activated forms like 5-MTHF (folate), methylcobalamin (B12), and pyridoxal-5-phosphate (B6).
1. Mikkelsen K, Apostolopoulos V. B Vitamins and Ageing. Subcell Biochem. 2018;90:451-70.
9. Yaku K, Okabe K, Nakagawa T. NAD metabolism: Implications in aging and longevity. Ageing Research Reviews. 2018 Nov;47:1-17.
10. Nazarali S, Kuzel P. Vitamin B Derivative (Nicotinamide)Appears to Reduce Skin Cancer Risk. Skin Therapy Lett. 2017 Sep;22(5):1-4.