Go to our Partner website

For you, if you are interested in supporting longevity at the cellular level

The amino acid formula of Essential Youth L-Ergothioneine can:
  • Help delay the aging process by slowing the rate of telomere shortening 
  • Provide efficient cellular protection against oxidative stress 
  • Support vision, heart, and overall cognitive health 

Ergothioneine is a food-derived amino acid found in certain mushrooms in high concentrations. It has the scientific community’s interest due to its cell-protective benefits and promising properties of supporting healthy aging.

image-two-column
Product details:
Health benefits at a glance:

First of all – what is ergothioneine? It’s an amino acid present throughout your body, but the levels have been shown to decline as we age. (1)  

You must get ergothioneine through your diet as the body can’t produce it, and it’s found in a variety of food sources, but the highest concentrations are in certain types of mushrooms.

This food-derived amino acid is thought to play a crucial role in supporting long-term health through its cell-protective benefits and inhibition of free radicals. (2)


Why it works:

Ergothioneine has the interest of the scientific community due to its properties that contribute to cell protection and its great promise in supporting healthy aging.

A new proprietary fermentation method has made it possible to provide supplementation of this nutrient. Studies have shown that the body has a specific mechanism to transport the amino acid ergothioneine into cells, indicating it’s crucial for overall health. (3,4)

Life Extension’s novel innovative formula can help maintain healthy ergothioneine levels to help ensure your body gets enough of this cell-protecting amino acid.


The science behind the product:

Healthy aging and longevity  

Studies indicate that ergothioneine can delay telomere shortening due to oxidative stress. (5) Your telomeres are like protective caps at the end of your chromosomes. As time goes by, these telomeres shorten naturally, in step with your aging process.

In a preclinical study, L-ergothioneine had a protective effect on telomere length and slowed the rate of telomere shortening under oxidative stress conditions, and in that supporting longevity. (5)

Cognitive and vision health

Low levels of ergothioneine in older adults have been linked with cognitive decline. In preclinical studies, ergothioneine showed beneficial neuroprotective properties from oxidative stress, supporting overall cognitive health. (1)

The cell-protecting properties of ergothioneine have also been linked to vision health. (6)

Supporting heart health

A 2020 clinical study found that higher ergothioneine levels were associated with healthier diets and with heart health. (7)

If mushrooms aren’t for you, you can still get the longevity-promoting benefits of ergothioneine with the innovative Essential Youth L-Ergothioneine formula. One daily capsule provides as much L-ergothioneine as 2 to 5 cups of white button mushrooms.


How to use:

Please take according to the dosage and use guidelines under supplement facts, or as recommended by a healthcare practitioner.

  1. Biochem Biophys Res Commun. 2016;478(1):162-167. 
  2. Cell Death Differ. 2010;17(7):1134-40. 
  3. Proc Natl Acad Sci U S A. 2005;102(14):5256-61.  Antioxidant & Redox Signaling 2017;26(5) 
  4. J Diet Suppl. 2020:1-14. 
  5. Indian Journal of Ophthalmology. 1982;30(5):441-443. 
  6. Heart. 2020;106(9):691-697.