Health Benefits at a Glance:
Life Extension® has partnered up with Insilico Medicine, Inc., who used artificial intelligence to identify piceatannol from passion fruit, trans-resveratrol, and garcinol from kokum fruit from a database of ingredients tested in human cell lines to support stem cell health.
Why it Works:
Stem cells are invaluable to health and vitality. This is because they can transform into other kinds of cells when the body needs them, a process called differentiation. Stem cells can also create more copies of themselves, which is called self-renewal. Both of these properties are essential to tissue rejuvenation.
A healthy balance between these two actions promotes healthy tissue maintenance, growth, and longevity. But aging can cause stem cells to no longer function optimally—often losing the ability to self-renew, or differentiate into other cells, or both.1 Thus GEROPROTECT® Stem Cell helps to maintain youthful, healthy stem cell function.
The Science Behind the Product:
Nutrients to encourage balanced stem cell health
GEROPROTECT® Stem Cell promotes youthful, healthy stem cell function and encourages balanced stem cell differentiation and self-renewal. It does so with nutrients that promote the cellular pathways that help maintain youthful stem cell behavior: a healthy, functional protein pool, DNA health, AMPK signaling, and more.
These compounds were identified in partnership with Insilico Medicine, Inc., a machine learning company whose proprietary algorithm is based on 21st Century artificial intelligence computing techniques.
Presveratrol™ is a proprietary blend of resveratrol and piceatannol, an extract of passion fruit. In vivo and in vitro studies indicate that piceatannol promotes stem cell differentiation as well as proteostasis—the quality control network that helps ensure the integrity of proteins within our cells.2-4
Resveratrol is a phytonutrient with well-known benefits for longevity and health. In vivo and in vitro studies indicate that resveratrol has beneficial effects on stem cell health.6,7
Additionally, the combination of resveratrol and piceatannol promotes DNA health as well as encourages the body’s natural pathways for managing senescent stem cells.8
Garcinol is a compound derived from the kokum (garcinia indica) fruit. In vitro studies indicate that garcinol helps to positively regulate healthy stem cell self-renewal and differentiation.9-11 Garcinol inhibits an enzyme called histone acetyltransferase, or HAT. This enzyme is part of a process called histone acetylation—one of the main causes of stem cell aging and loss of function. By inhibiting this enzyme, garcinol helps restore youthful stem cell function and longevity.
How to Use:
- Take two (2) capsules daily, with or without food, or as recommended by a healthcare practitioner.
Serving Size: 2 vegetarian capsule
Amount Per Serving:
|Livinol™ kokum extract (fruit) [std. to 20% garcinol]||500 mg|
|Presveratrol™ Proprietary Blend||378 mg|
|[passion fruit extract (seed) (std. to 3.5% piceatannol) and Japanese knotweed extract (root) (std. to 98% trans-resveratrol)]|
Other Ingredients: microcrystalline cellulose, cyclodextrin, vegetable cellulose (capsule), rice concentrate, silica.
†Developed in collaboration with Insilico Medicine, Inc.
Livinol™ is a trademark of Sabinsa Corporation.
Dosage and Use:
Take two (2) capsules daily, with or without food, or as recommended by a healthcare practitioner.
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
A food supplement should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Store tightly closed in a cool and dry place.
Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews.