Enhanced Zinc Lozenges

Defense against seasonal immune challenges

Item #01961 18,75 mg 30 Vegetarian Lozenges 1 per serving In Stock

Enhanced Zinc Lozenges

Defense against seasonal immune challenges

Item #01961 18,75 mg 30 Vegetarian Lozenges 1 per serving In Stock

For you, if you are interested in supporting your immune system

The ingredients in Enhanced Zinc Lozenges can:
  • Release positively charged zinc ions for occasional immune system support
  • Contribute to strengthening your immune system during the fall and winter season
  • Come as naturally flavored peppermint lozenges

Zinc Acetate found in Enhanced Zinc Lozenges can contribute to building a stronger immune system which is essential to your immune system's ability to defend against invaders. 

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Product details "Enhanced Zinc Lozenges"
Health benefits at a glance:

Zinc acetate found in Enhanced Zinc Lozenges can contribute to defending against seasonal immune challenges. 

Zinc acetate releases positively charged zinc ions which support your immune system. Meant for occasional short term use when seasonal changes expose the immune system. 


Why it works:

Most people have probably tried avoiding a cold during the winter season. If such a cold arises, it is always easier to inhibit such an issue when the first signs are showing. However, this is best done with an immune system that functions optimally, so it may deal with invaders accordingly. 

Zinc stimulates around 300 enzymes in the body and simultaneously fortifies the immune system, and zinc acetate lozenges have been shown to support the immune function [1-3]. 

Life Extension® Enhanced Zinc Lozenges provide zinc acetate with no other ingredients that could reduce the delivery of immune-supporting, positively charged zinc ions. On top of that, Enhanced Zinc Lozenges taste good because they come in a naturally flavored peppermint lozenge.


The science behind the product:

Zinc has many positive impacts on the human health, ranging from contributing to effective immune defenses to promoting optimal growth and development of the human body [4]. Zinc is one of the most common elements in the body and is essential to the functioning of over 300 processes involving enzymes and hormones [5].

Furthermore, zinc is also an essential component of one of the body’s most important natural antioxidants, the enzyme known as copper/zinc superoxide dismutase (Cu/Zn SOD) [6,7]. 

Cu/Zn SOD is a member of a specific family of antioxidant enzymes which inhibits dangerous superoxide radicals, which can damage lipids, proteins, and DNA [8,9]., Cu/Zn SOD breaks down these radicals and convert them into hydrogen peroxide, which is in turn converted to water and oxygen [10].

Zinc also plays a crucial role in supporting the immune function [11-15] Zinc helps maintain a type of white blood cells called T-lymphocytes which job it is to fight infections.

It is estimated that more than 200 distinct viruses target the respiratory tract, which can cause common complaints. [16]. Zinc interferes with the viruses’ ability to gain a foothold in the respiratory tract, which, according to several clinical trials with hundreds of patients, may in turn prevent seasonal problems. [17].


How to use:
  • Completely dissolve in mouth one (1) lozenge every 2 wakeful hours, not to exceed 8 lozenges per day, or as recommended by a healthcare practitioner.
  • Do not use for more than 3 consecutive days.
  • Do not chew or swallow lozenge.
  • May cause nausea if taken on empty stomach.
Supplement Facts

Serving size 1 vegetarian lozenge

Servings per container 30

Amount per serving



Total Carbohydrate

5 g


4 g

Zinc (as zinc acetate)

18.75 mg

Other ingredients: dextrose, peppermint flavor, stearic acid, vegetable stearate, silica.

Dosage and use
  • Completely dissolve in mouth one (1) lozenge every 2 wakeful hours, not to exceed 8 lozenges per day, or as recommended by a healthcare practitioner.
  • Do not use for more than 3 consecutive days.
  • Do not chew or swallow lozenge.
  • May cause nausea if taken on empty stomach.

Supplemental zinc can inhibit the absorption and availability of copper. If more than 50 mg of supplemental zinc is taken daily on a chronic basis, 2 mg of supplemental copper should also be taken to prevent copper deficiency. Chronic ingestion of more than 100 mg of zinc daily may be immunosuppressive for some aspects of T-cell and NK cell function.


Do not purchase if outer seal is broken or damaged.
If you are undergoing treatment for a medical condition or if you are pregnant or lactating, please consult with your medical practitioner first.

A food supplement should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Store tightly closed in a cool and dry place.


  1. Curr Ther Res. 1998;59:595–607.
  2. Ann Intern Med. 2000;133:245-52.
  3. J Infect Dis. 2008;197:795-802.
  4. Grungreiff K, Reinhold D. Liver cirrhosis and “liver” diabetes mellitus are linked by zinc deficiency. Med Hypotheses. 2005;64(2):316-7.
  5. Prasad AS. Zinc: the biology and therapeutics of an ion. Ann Intern Med. 1996 Jul 15;125(2):142-4.
  6. Kasperczyk S, Birkner E, Kasperczyk A, Zalejska-Fiolka J. Activity of superoxide dismutase and catalase in people protractedly exposed to lead compounds. Ann Agric Environ Med. 2004;11(2):291-6.
  7. Kocaturk PA, Kavas GO, Erdeve O, Siklar Z. Superoxide dismutase activity and zinc and copper concentrations in growth retardation. Biol Trace Elem Res. 2004;102(1-3):51-9.
  8. Landis GN, Tower J. Superoxide dismutase evolution and life span regulation. Mech Ageing Dev. 2005 Mar;126(3):365-79.
  9. Noor R, Mittal S, Iqbal J. Superoxide dismutase—applications and relevance to human diseases. Med Sci Monit. 2002 Sep;8(9):RA210-5.
  10. Kato S, Saeki Y, Aoki M, et al. Histological evidence of redox system breakdown caused by superoxide dismutase 1 (SOD1) aggregation is common to SOD1-mutated motor neurons in humans and animal models. Acta Neuropathol (Berl). 2004 Feb;107(2):149-58.
  11. Raqib R, Roy SK, Rahman MJ, et al. Effect of zinc supplementation on immune and inflammatory responses in pediatric patients with shigellosis. Am J Clin Nutr. 2004 Mar;79(3):444-50.
  12. Bogden JD. Influence of zinc on immunity in the elderly. J Nutr Health Aging. 2004;8(1):48-54.
  13. Field CJ, Johnson IR, Schley PD. Nutrients and their role in host resistance to infection. J Leukoc Biol. 2002 Jan;71(1):16-32.
  14. Chandra RK. Impact of nutritional status and nutrient supplements on immune responses and incidence of infection in older individuals. Ageing Res Rev. 2004 Jan;3(1):91-104.
  15. Fraker PJ, King LE. Reprogramming of the immune system during zinc deficiency. Annu Rev Nutr. 2004;24:277-98.
  16. Mossad SB, Macknin ML, Medendorp SV, Mason P. Zinc gluconate lozenges for treating the common cold. A randomized, double-blind, placebo-controlled study. Ann Intern Med. 1996 Jul 15;125(2):81-8.
  17. Hulisz D. Efficacy of zinc against common cold viruses: an overview. J Am Pharm Assoc (Wash.DC.). 2004 Sep;44(5):594-603.
  18. Anzueto A, Niederman MS. Diagnosis and treatment of rhinovirus respiratory infections. Chest. 2003 May;123(5):1664-72.
  19. Eby GA. Zinc lozenges: cold cure or candy? Solution chemistry determinations. Biosci Rep. 2004 Feb;24(1):23-39.
  20. McElroy BH, Miller SP. An open-label, single-center, phase IV clinical study of the effectiveness of zinc gluconate glycine lozenges (Cold-Eeze) in reducing the duration and symptoms of the common cold in school-aged subjects. Am J Ther. 2003 Sep;10(5):324-9.
  21. McElroy BH, Miller SP. Effectiveness of zinc gluconate glycine lozenges (Cold-Eeze) against the common cold in school-aged subjects: a retrospective chart review. Am J Ther. 2002 Nov;9(6):472-5.
  22. Prasad AS, Fitzgerald JT, Bao B, Beck FW, Chandrasekar PH. Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2000 Aug 15;133(4):245-52.

Original source/product from Life Extension®