GABA (Gamma-Aminobutyric Acid)

Health benefits at a glance:

First of all, what is GABA? It is a naturally occurring amino acid, clinically studied for its ability to relieve occasional stress while promoting a relaxed state of mind. 

Doctor’s visits, public speaking, and job interviews all share one thing: they can stir up stress or worry. Unlike standard stress relief supplements, GABA can promote a calm response to stress in as little as 30 minutes.

The supplement is gluten-free, vegetarian, and non-GMO.

Why it works:

Gamma-aminobutyric acid (GABA) is produced in the body and serves as the brain’s main inhibitory neurotransmitter. It helps regulate the brain’s “let’s go” (excitatory) and “slow down” (inhibitory) signals, keeping communication between neurons in balance. By maintaining healthy GABA levels, the brain is better equipped to handle life’s stressors.

Life Extension’s GABA (Gamma-Aminobutyric Acid) can ease tension, promote relaxation and calm, a balanced mood, and healthy sleep without that drowsy feeling the next day.

The science behind the product:

Help your body respond to anticipated stress

Demanding situations like job interviews, medical appointments, public speaking, upcoming travels, etc., can bring on stress that impacts your well-being. This high-quality supplement with clinically studied GABA, derived from Lactobacillus hilgardii K-3 fermentation, can promote a healthy response to such occasional stress.

Occasional stress and GABA

In a placebo-controlled clinical trial, healthy participants with a self-reported fear of heights took 100 mg of GABA before crossing a suspension bridge. (1) Researchers evaluated their stress response by measuring levels of salivary immunoglobulin A (IgA), an immune protein that typically decreases during stressful situations. (2-5) Results showed that those who took GABA maintained normal salivary IgA levels compared to placebo. (1)

GABA and challenging tasks

Stressful mental tasks can be demanding. In a single-blind, randomized, crossover, placebo-controlled study, participants faced a combined stress load: A 10-minute arithmetic test plus a 5-minute auditory target detection task (DT). Three sessions were conducted at approximately 10, 40, and 70 minutes after participants took either 100 mg of GABA or a placebo. (6)

Then a subjective survey evaluated six dimensions of stress, including tension and anger. Researchers also recorded participants’ brainwave activity. (6)

Those who took GABA reported feeling less strained after completing the tasks compared to placebo. Brainwave data also indicated a healthy physiological stress response in the GABA group. (6)

“Fight-or-flight” reaction and heart rate

In another randomized, double-blind, crossover, placebo-controlled study, also using an arithmetic stress test, heart rate was measured to determine sympathetic and parasympathetic nervous system activity after GABA intake. (7) The results showed that GABA produced a quick return to a healthy baseline following the stress response.

GABA for better sleep support*

GABA can also influence sleep. In a double-blind, randomized, placebo-controlled trial, healthy adults aged 24–57 took 100 mg of GABA 30 minutes before bedtime. (8) Over one week, multiple sleep quality index scores were collected. Individuals in the GABA group reported falling asleep more quickly than those taking a placebo, and they did not experience next-day drowsiness. (8)

*For occasional sleeplessness

Take it slow with GABA when you need it most! 

How to use:

Please take according to the dosage and use guidelines under the supplement facts, or as recommended by a healthcare practitioner. 

FAQ

What is inside GABA?

Each capsule delivers 100 mg of PharmaGABA®, a clinically studied, trademarked form of gamma-aminobutyric acid (GABA).

What is GABA, and how does it work?

Gamma-aminobutyric acid (GABA) is a key inhibitory neurotransmitter that helps balance excitatory (“start”) and inhibitory (“stop”) signalling between brain cells. By supporting this balance, GABA promotes a sense of calm. Life Extension’s formula provides clinically studied GABA, derived from the natural fermentation of Lactobacillus hilgardii K-3, to help ease occasional stress, support mood balance, and promote healthy sleep.

Who is GABA for?

This supplement is ideal for anyone looking for quick relief from occasional stress. GABA can also encourage a relaxed state of mind and provide sleep support.

When can I expect results?

In clinical studies, GABA supported a healthy stress response within just 30 minutes, while sleep benefits were observed after one week of use. Individual experiences may vary, as everyone responds differently.

When is the best time to take GABA? Should it be with food or on an empty stomach?

If you expect a stressful situation, take one capsule as needed, any time of day, with or without food, up to twice daily. Always follow the directions on your supplement label for proper use.

Can this supplement interact with my medication?

There is no evidence to suggest that the nutrients in this formula would negatively interact with prescription medications. However, it is always recommended to inform your healthcare provider about any supplements you are taking.

Has this product been tested for quality and safety?

All Life Extension’s raw materials and finished products undergo rigorous testing to ensure they meet their high-quality standards. This includes testing for heavy metals, microbes, disintegration, potency, and active ingredient content. Products are only approved for production after meeting Life Extension’s specifications.

Does this supplement contain allergens?

Life Extension’s GABA is free from milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, sesame, and soybeans.

Where is this product produced?

This supplement is manufactured in the USA in a facility that complies with GMP standards (“good manufacturing practices”).

Is this product vegetarian?

Yes, this product is vegetarian and does not contain any animal-derived ingredients.

Is this product gluten-free?

Yes, this supplement is gluten-free.

Is this product non-GMO?

Yes, this product and all its ingredients are Life Extension verified non-GMO.

Can children take this product?

This formula was designed for adults over the age of 18. Always consult with your child’s physician before giving them any supplements.