Health benefits at a glance:

Immune Senescence Protection Formula™ can provide comprehensive immune senescence protection and was created for year-round support of the immune systems.

Why it works:

Due to age, our immune system declines. An imbalance between certain immune cell populations develops, involving a surplus of so-called memory T cells that go after known invaders and a deficit of so-called naïve T cells that attack new invaders.

The final result is a less-vigilant defense system – or immune senescence, which contributes to the problems of aging.

Life Extension® researchers have designed an innovative formula to help rebalance the major arms of the aging immune system. Immune Senescence Protection Formula™ provides three potent immune supporting ingredients cistanche, reishi mushroom, and pu-erh tea extract .

The science behind the product:

This formula focuses on supporting three types of immune cells: naïve T cells, memory T cells and natural killer (NK) cells. Naïve T cells attack new invaders. (1) Memory T cells attack previously-known invaders. (2) NK cells function as your body’s first responders. (3) 

When a naïve T cell encounters a new threat, it remembers it, becoming a memory T cell. This means we naturally develop a surplus of memory T cells over time. (4) 

In order to maintain a healthy immune system, we need to support a youthful ratio of naïve to memory T cells, promote healthy naïve T cell production, and encourage NK cell activity.

Rejuvenating the immune system with cistance 

The cistanche plant contains a compound called echinacoside. It can stimulate naïve T cell development, which in turn supports a healthy ratio of naïve-to-memory T cells. (5,6) 

Cistanche can also increase NK cell activity. In pre-clinical research, cistanche supported a 15% life span increase for NK cells. (5)

In a 12-week clinical study, standardized cistanche produced an 11.7% increase in NK cell activity and a 20.2% improvement in the ratio of CD4 to CD8 cells, an indicator of youthful, healthy immune response. (7)

Inhibiting immune senescence with reishi mushroom

Pre-clinical research indicates that reishi mushroom's bioactive compounds may help inhibit the factors of immune senescence and promote longevity. (8,9)  These extracts strengthen the immune system’s first line of defense by boosting the function of innate immune cells.

This species is packed with polysaccharides, triterpenes and other compounds that boost the function of hematopoietic stem cells, T cells and other essential immune factors that serve as your body’s defense, thus inhibiting immune senescence and promoting longevity.  (8,10)

Supporting immune balance with pu-erh tea extract

Pu-erh tea is made from the same plant as black and green tea. Although, this kind of tea is different; it’s rich in polyphenols and other bioactive molecules that support immune health.

In a pre-clinical study, pu-erh extract produced a 7% increase in NK cells and a 10% increase in naïve T cells. 

In the same study, pu-erh tea extract promoted healthy bone marrow function, which helps rebuild peripheral immune cell components. (11)

How to use:

Please take according to the dosage and use guidelines under supplement facts, or as recommended by a healthcare practitioner.