Morosil: the natural path in achieving a healthy weight

Life Extension Europe: closeup of moro orange fruit, red coloured juicy fruit fibres.

Morosil is a potent extract derived from Sicilian Moro blood oranges, with ability to facilitate weight loss and reduce harmful abdominal fat. 

Over half of the adult population in Europe falls into the overweight or obese category (1). However, it's important to note that not all fat is created equal, with abdominal fat presenting the most significant health risk. This type of fat contributes to a state of chronic inflammation in the body, linked to a higher likelihood of developing metabolic disorders (2).

Research highlights that ongoing inflammation is a major risk factor for a range of serious conditions, including cardiovascular diseases, metabolic syndrome, diabetes, and cancer. 

For years, Life Extension Europe has aimed to inform its readers about the perils of chronic inflammation and the importance of effective management strategies to mitigate these risks.

Moro oranges are held in high regards in the Mediterranean. They are well-known for their high anthocyanin content and a variety of beneficial compounds. They can be an aid in weight management when combined with exercise and a balanced diet.

What is Morosil?

MoroSil® is a patented extract backed by clinical research.

Replicating the outcomes of earlier studies typically requires fresh moro blood orange juice, a high-calorie and labor-intensive option. (3)

The extraction meticulously ensures the preservation of the orange juice's rich natural composition of anthocyanins, hydroxycinnamic acids, flavone glycosides, and ascorbic acid. 

Supplementing with Morosil 

Morosil has further been proven in clinical trials to effectively reduce waist and hip measurements over both short and long durations. 

Life Extension's gummies incorporate Morosil and offer a logical alternative supported by solid clinical evidence. (4) 

In a specific trial, 60 overweight participants consumed 400 mg of the extract daily for twelve weeks without altering their daily calorie intake of 1,500-2,000 or their exercise habits. 

The result was a significant reduction in waistline by 7 centimeters and hips by nearly 6 centimeters, outperforming the placebo group substantially. (4)

Clinical trials have further validated Morosil's potential in human weight loss efforts:

  • In one study, participants taking 400 mg of Moro orange juice extract daily for 12 weeks saw a 4% reduction in weight, a decrease in waist and hip circumference, and improvements in BMI. 
  • Another trial involving a longer, six-month period and a calorie-reduced diet coupled with regular walking demonstrated even more profound effects on weight, fat mass, abdominal fat, visceral fat, and subcutaneous fat, with 36% of participants achieving more than a 5% weight loss.

The moro orange

Moro orange is a Mediterranean fruit which is known to promote the loss of belly fat.

Moro orange in fact has multiple weight loss benefits. Clinical studies showed that moro orange extract can reduce weight by an average of 4.2% and decrease the particularly dangerous type of belly fat when combined with exercise and a reduced-calorie diet. (5)

This is down to moro orange being high in anthocyanins, which some data have linked to weight loss, along with an array of other beneficial compounds.

However not anthocyanins alone. The anti-obesity effects of moro orange extract are attributed to its total unique blend of health-promoting compounds. 

These other health-promoting compounds the more orange contains includes: (6)

  • Flavonoids
  • Carotenoids
  • Hydroxycinnamic acids

They have been shown to: (6) 

  • Inhibit fat storage
  • Decrease fat accumulation by about 50%
  • Modulate gene expression in adipose tissue

Alternative weight management supplements

Everyone's body reacts differently, meaning a supplement aiding in a friend's weight loss might not have the same effect on you, morosil supplements included. 

Here are a few alternatives to explore:

  • Capsaicin supplements, derived from red chili, are known to support fat burning through thermogenesis.
  • An AMPK activator could also be beneficial. AMPK, an enzyme that, when increased in the body, may boost fat burning, especially around the abdomen.


Morosil stands as a promising natural solution for those aiming to combat obesity and minimize abdominal fat. 

Its efficacy, backed by human studies, showcases significant reductions in weight, BMI, and waist circumference, underscoring morosil as a crucial component of a healthy weight-loss strategy. 

With its rich content of anthocyanins and other synergistic compounds, morosil offers a natural, effective path to achieving a healthier physique mitigating the risks associated with abdominal fat.

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  1. https://www.euronews.com/health/2023/12/20/europes-growing-obesity-crisis-which-countries-have-the-most-and-least-overweight-populati
  2. Cardile V, Graziano AC, Venditti A. Clinical evaluation of Moro (Citrus sinensis (L.) Osbeck) orange juice supplementation for the weight management. Nat Prod Res. 2015;29(23):2256-60.
  3. http://morosil.bionap.com
  4. Nat Prod Res. 2015;29(23):2256-60.
  5. Titta L, Trinei M, Stendardo M, et al. Blood orange juice inhibits fat accumulation in mice. Int J Obes (Lond). 2010 Mar;34(3):578-88. 
  6. Azzini E, Giacometti J, Russo GL. Antiobesity Effects of Anthocyanins in Preclinical and Clinical Studies. Oxid Med Cell Longev. 2017;2017:2740364.